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Cisplatin drugbank

WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research ... Thioredoxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M phase arrest. Invest New Drugs. 2011 Aug;29(4):627 ... WebGeneric Name Ondansetron DrugBank Accession Number DB00904 Background. A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Early clinical studies with cis-diammine-1,1-cyclobutane ... - DrugBank

WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... we treated cisplatin damaged neuroblastoma cells with a pharmacological ROCK inhibitor (Y27632) or sham, and monitored cell survival, accumulation of a chemoresistant phenotype, and in vivo tumor … WebCisplatin Prices, Coupons and Patient Assistance Programs. Cisplatin is a member of the alkylating agents drug class and is commonly used for Anal Cancer, Bladder Cancer, … gaga haus eyeliner for waterline https://new-lavie.com

Sofosbuvir: Uses, Interactions, Mechanism of Action

WebGeneric Name Digoxin DrugBank Accession Number DB00390 Background. Digoxin is one of the oldest cardiovascular medications used today. 5 It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. 7 Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. 25 This drug originates … WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. Structured drug data for data science & ML. ... Cisplatin (DB00515) Docetaxel (DB01248) Erlotinib (DB00530) Filgrastim (DB00099) Pegfilgrastim (DB00019) WebDec 31, 2015 · Generic Name Levofloxacin DrugBank Accession Number DB01137 Background. Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. 1 It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin 1 and remains … gaga haus the black eyeliner

Arsenic trioxide and cisplatin synergism increase cytotoxicity in …

Category:Combined expression of multidrug resistance protein (MRP) and ...

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Cisplatin drugbank

Platinum Compounds DrugBank Online

WebPubMed Central (PMC) WebOct 30, 2015 · DrugBank Accession Number DB09293 Background. Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of …

Cisplatin drugbank

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WebDaunorubicin is an anthracycline antibiotic and antineoplastic agent. 5 It acts by inhibiting cellular reproduction through interference with DNA replication although it may contribute to the induction of cell death by increasing oxidative stress through the generation of reactive oxygen species and free radicals. WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... Arsenic trioxide and cisplatin synergism increase cytotoxicity in human ovarian cancer cells: therapeutic potential for ovarian cancer. Cancer Sci. 2009 Dec;100(12):2459-64. doi: 10.1111/j.1349 …

WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... Regulation of copper transporter 2 expression by copper and cisplatin in human ovarian carcinoma cells. Mol Pharmacol. 2010 Jun;77(6):912-21. doi: 10.1124/mol.109.062836. Epub 2010 Mar 1. PubMed ID. WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin. Biochem Pharmacol. 1998 Oct 15;56(8):1013-21.

WebDurvalumab (בתעתיק עברי: דורוואלומאב; שם מסחרי: Imfinzi) היא תרופה המאושרת על ידי ה-FDA, לטיפול בסרטן שפותחה על ידי חברת Medimmune\Astrazenica.זהו נוגדן מונוקלונאלי אנושי (Immunoglobulin G1 Kappa(IgG1k)), אשר חוסם את האינטראקציה בין החלבון החוץ תאי PD-1 ... WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... (CBDCA, JM8), an analogue of cisplatin showing reduced toxicity in preclinical studies, was evaluated in 60 patients. Doses were given initially every 3 weeks and escalated from 20 to 520 mg/m2. Following …

WebGeneric Name. Sofosbuvir. DrugBank Accession Number. DB08934. Background. Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is …

WebThe present findings suggest that induction of P450 by cisplatin may take part in the renal injury or nephrotoxicity of cisplatin. DrugBank Data that Cites this Article Drug Enzymes. Drug Enzyme Kind Organism Pharmacological Action Actions; Cisplatin: Cytochrome P450 4A11: Protein: Humans: gagah happy hound storeWebMar 29, 2024 · Reviewed on 3/29/2024. Cisplatin: An anticancer drug that belongs to the family of drugs called platinum compounds. Cisplatin is used in the treatment of a wide … gaga hershey ticketsWebGeneric Name Adalimumab DrugBank Accession Number DB00051 Background. Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor. 2,3 It was originally launched by Abbvie in the U.S. and approved in 2002 by the … gaga height and weightWebBaricitinib. Baricitinib is a Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. gaga heightWebDrugBank Accession Number DB05773 Background. Trastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to … gaga hershey parkWebCisplatin is the prototype platinum coordination complex classified as an alkylating agent and used intravenously in the treatment of several forms of cancer. Cisplatin has been associated with a low rate of serum enzyme elevations and with rare cases of clinically apparent, acute liver injury. black and white moon pngCisplatin DrugBank Accession Number DB00515 Background. Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and … See more black and white moon images