2024 Cisplatin-based combination chemotherapy

Cisplatin-based combination chemotherapy

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August undefined, 2024

WebCisplatin based combination therapy can in these indications prolong the survival in 30-40% of patients. The role of carboplatin in malignant lymphoma is not clear yet and is … WebNational Center for Biotechnology Information

Cisplatin (chemotherapy drug) - treatment and side effects

WebOct 2, 1997 · Treatment usually consists of combination chemotherapy. Cisplatin-Based Regimens During the 1980s, two- or three-drug regimens, typically based on the use of cisplatin (Platinol) in combination with a Vinca alkaloid, were shown to result in overall response rates of approximately 30%. WebTherapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new … library cash

Cisplatin - an overview ScienceDirect Topics

Web1 day ago · KEYTRUDA, in combination with enfortumab vedotin, is indicated for the treatment of patients with locally advanced or metastatic urothelial carcinoma (mUC) who … WebAs in the clinic cisplatin is coadministered as a combination with other chemotherapeutic substances, cross-resistance of LTTs towards gemcitabine and doxorubicin was determined. Interestingly, a 16-fold cross-resistance to gemcitabine in RT-112-LTT and a 2.1-fold cross-resistance to doxorubicin in T-24-LTT were observed ( Table S1 ). 2.2. Webwith solid tumors receiving cisplatin-based highly emetogenic chemotherapy (HEC). Support Care Cancer. 2015 Oct;23(10):2917–23. ... Kosaka Y, Okita K, Yuki S, et al. One-Day Versus Three-Day Dexamethasone in Combination with Palonosetron for the Prevention of Chemotherapy-Induced Nausea and Vomiting: A Systematic Review and … library/cash

Adjuvant Chemotherapy - an overview ScienceDirect Topics

Nanocarriers containing platinum compounds for combination chemotherapy

WebNov 2, 2024 · One of the most frequently used categories is called platinum-based chemotherapy drugs. They include: cisplatin oxaliplatin carboplatin These medications are often used in combination with... WebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 … library cataloging courses onlineWebChemotherapy consisted of cisplatin-based combination treatment and radiotherapy was given as whole-brain irradiation of 30 to 40 Gy and in single cases combined with a boost of 10 Gy to single lesions. Results: Overall, 10 patients achieved long-term survival (23%; 95% confidence interval [CI], 10.1% to 35.4%). library cash flow projection sample

"WebApr 12, 2024 · Progression-free survival (PFS) was 8 and 5 months in the cisplatin plus gemcitabine cohort and the gemcitabine cohort (p < .001), respectively. 4 Based on the … " - Cisplatin-based combination chemotherapy

Cisplatin-based combination chemotherapy

Biomarkers for chemotherapy and drug resistance in the …

WebOct 17, 2012 · Combination cisplatin-based chemotherapy could be a viable option for patients of good performance status with recurrent/metastatic cervical cancer, but further trials that report adequate survival and QoL data are sought. Response rates and improvements in survival are low. Cisplatin-based combinat … Web1 day ago · Metabolites of melatonin can also serve protective roles against DNA damage, but while combined with chemotherapeutic agents, including doxorubicin, cytarabine, daunorubicin, and etoposide, melatonin exerts a synergistic effect on inducing cytotoxicity and apoptosis in cancer cells [26]. Table 2. Chemotherapy related MMR mutations

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WebJan 12, 2024 · New combination chemotherapy of cisplatin with an electron-donating compound for treatment of multiple cancers Scientific Reports Article Open Access … WebIntroduction of cisplatin based chemotherapy has revolutionized the treatment of germ cell tumors. A common side effect of multiday cisplatin chemotherapy is severe nausea and vomiting. Considerable progress has been made in the control of these side effects since the introduction of cisplatin based chemotherapy in the 1970s.

WebComparison of single agent versus combined chemotherapy in previously treated patients with advanced urothelial carcinoma: a meta-analysis Xiao-Jun Wu, Yi Zhi, Peng He, Xiao-Zhou Zhou, Ji Zheng, Zhi-Wen Chen, Zhan-Song Zhou Institute of Urinary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, People’s Republic of … WebCisplatin Vial. - Uses, Side Effects, and More. Cisplatin may cause severe kidney problems, nerve problems, and severe nausea and vomiting. Nerve problems may occur …

WebCisplatin, a chemotherapy drug, is best known for curing testicular cancer. It is also used in the treatment of a wide range of other cancers, including lung, bladder, cervical, and ovarian cancers. Cisplatin and other similar … WebCisplatin-based chemotherapy (CBC) is highly efficacious for advanced cervical cancer; its efficacy can be enhanced by combining with 15 mg/kg (standard dose) bevacizumab (BEV). However, this standard dose is associated with various adverse events (AEs).

WebFeb 22, 2024 · There are many combinations of chemotherapy drugs used to treat cancer. Solid Tumors Combination chemotherapy is used with several types of solid tumors. An example with lung cancer is using the combination of Platinol (cisplatin) and Navelbine (vinorelbine) to treat non-small cell lung cancer. 4

WebMay 23, 2024 · Four common combinations of chemotherapy drugs for SCLC include: cisplatin and etoposide. carboplatin (Paraplatin) and etoposide. cisplatin and irinotecan … library cataloging for dummiesWebDec 11, 2024 · Currently, the standard antiemetic therapy for cisplatin—a highly emetogenic chemotherapy agent—involves triplet-combination therapy with a 5-hydroxytryptamine-3 (5-HT3) receptor antagonist, neurokinin-1 (NK1) receptor antagonist, and dexamethasone. library castlebarWebNov 8, 2024 · Cisplatin-based combination chemotherapy has obtained some progress in the clinic. For example, cisplatin combined with etoposide or irinotecan for lung cancer; cisplatin combined with 5-fluorouracil, or gemcitabine, or paclitaxel for head and neck cancer ( Gerweck, 2000; Chou, 2006; Liu et al., 2024; Yu et al., 2024 ). library case cryptoWebAmong the three paclitaxel‐based combination regimens, symptomatic radiation pneumonia was significantly increased in TC and TF on weekly regimens compared with … library cart with sloping shelvesWebSep 21, 2016 · Cisplatin-based chemotherapy during pelvic radiation therapy improves long-term PFS and OS among locally advanced cervical cancer patients collectively and … library carts for movingWebDec 11, 2024 · Combination treatment with Tmab and nabPTX demonstrated a promising anti-tumor effect without any severe adverse effects. In the absence of definitive clinical trials, which are unlikely to be performed due to the rarity of this tumor, we believe that our case report suggests a potential utility of Tmab-based chemotherapy for HER2-positive … mcintosh mc 2100 power ampWebChemoradiotherapy with paclitaxel liposome plus cisplatin for locally advanced esophageal squamous cell carcinoma: A retrospective analysis - PMC Back to Top Skip to main content An official website of the United States government Here's how you know The .gov means it’s official. Federal government websites often end in .gov or .mil. library cataloging jobs